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Recombinant Rabbit Coagulation Factor IX (F9), N-His
Product Overview
BioVenic's Recombinant Rabbit Coagulation Factor IX (F9), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 29.7 kDa. The purity is> 80%.
Specifications
Target Information
Rabbit Coagulation Factor IX (F9) is a vitamin K-dependent plasma protein that plays a crucial role in the intrinsic pathway of blood coagulation. It is activated to factor IXa, which then converts factor X to its active form (factor Xa) in the presence of calcium ions and membrane phospholipids, ultimately leading to thrombin formation and clot stabilization. In rabbits, as in other mammals, deficiency in factor IX can lead to severe bleeding disorders similar to hemophilia B in humans. This highlights its essential role in maintaining hemostasis and preventing excessive bleeding. Additionally, factor IX is involved in various animal models of thrombosis, indicating its importance in both physiological and pathological clotting processes.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.