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Recombinant Rabbit C-C Motif Chemokine 2 (CCL2), N-His
Product Overview
BioVenic's Recombinant Rabbit C-C Motif Chemokine 2 (CCL2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 12.7 kDa. The purity is> 97%.
Specifications
Target Information
Rabbit C-C Motif Chemokine 2 (CCL2), also known as Monocyte Chemoattractant Protein-1 (MCP-1), is a key chemokine involved in immune responses and inflammation. It acts as a ligand for C-C chemokine receptor CCR2 and induces chemotaxis in monocytes, macrophages, and T cells. CCL2 plays a crucial role in recruiting these immune cells to sites of inflammation, facilitating the body's response to infection and tissue injury. Additionally, CCL2 has been implicated in various diseases, including atherosclerosis and neuropathic pain. In rabbits, CCL2 has been shown to enhance macrophage chemotaxis and osteogenesis during bone regeneration. Its ability to modulate immune cell migration and promote tissue repair makes CCL2 a valuable target for research in inflammatory and immune-related diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.