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Recombinant Rabbit Brain-Derived Neurotrophic Factor (BDNF), N-His

Cat. No.AP4C397

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Rabbit Brain-Derived Neurotrophic Factor (BDNF), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 19.7 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Oryctolagus cuniculus (Rabbit)
Expression System E.coli
Purity > 97%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 19.7 kDa
Physical State Lyophilized
Formulation 20 mM Tris, 150 mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Rabbit Brain-Derived Neurotrophic Factor (BDNF) is a key neurotrophin that supports neuronal survival, growth, and differentiation. It binds to the high-affinity receptor TrkB, activating signaling pathways such as MAPK, PLCγ, and PI3K/Akt, which are crucial for synaptic plasticity and learning and memory. BDNF is widely expressed in the central nervous system (CNS) and plays a significant role in neuroprotection, particularly against conditions like cerebral ischemia and neurotoxicity. In rabbits, BDNF has been studied for its potential in promoting neuronal recovery and synaptic plasticity, making it a valuable target for research in neurodegenerative diseases and neural repair. Additionally, BDNF's involvement in energy homeostasis and its regulatory effects on glucose metabolism highlight its importance in metabolic processes.

Protein Rabbit Brain-Derived Neurotrophic Factor (BDNF)
Protein Synonym BDNF
Gene ID 100356949
EC No. A0A5F9CTM1

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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