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Recombinant Rabbit Angiopoietin 2 (ANGPT2), N-His
Product Overview
BioVenic's Recombinant Rabbit Angiopoietin 2 (ANGPT2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 32.9 kDa. The purity is> 97%.
Specifications
Target Information
Rabbit Angiopoietin 2 (ANGPT2) is a key regulator of vascular stability and angiogenesis. It antagonizes the effects of Angiopoietin 1 (ANGPT1) by binding to the TIE2 receptor, leading to destabilization of blood vessels and promoting inflammation and vascular leakage. In addition to its role in vascular homeostasis, ANGPT2 has been implicated in pathological conditions such as sepsis and COVID-19, where it contributes to hypercoagulation and endothelial dysfunction. In rabbits, ANGPT2 could be a valuable model for studying these processes and developing therapeutic strategies to counteract its detrimental effects in disease states.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-0.5 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.