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Recombinant Rabbit Alpha-2-Plasmin Inhibitor, N-His
Product Overview
BioVenic's Recombinant Rabbit Alpha-2-Plasmin Inhibitor, N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 57.7 kDa. The purity is> 95%.
Specifications
Target Information
Rabbit Alpha-2-Plasmin Inhibitor (a2PI) is a significant protein that acts as a major inhibitor of plasmin, an enzyme responsible for degrading fibrin and various other proteins. This protein plays a crucial role in regulating the blood clotting pathway, ensuring that blood clots are stable and preventing excessive fibrinolysis. In medical research, understanding the function of a2PI is vital for studying conditions related to blood clotting and fibrinolysis. For example, mutations in the gene encoding this protein can lead to disorders associated with abnormal blood clotting. Additionally, a2PI has applications in research related to thrombosis and hemostasis, where it helps in elucidating the mechanisms of blood clot formation and dissolution. Its role in maintaining the balance between clotting and fibrinolysis makes it an important target for therapeutic interventions aimed at treating or preventing thrombotic disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.