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Recombinant Porcine Hepcidin (Hepc), N-His-GST
Product Overview
BioVenic's Recombinant Porcine Hepcidin (Hepc), N-His-GST is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 36.5 kDa. The purity is>95% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.
Specifications
Target Information
Hepcidin antimicrobial peptide is encoded by the HAMP gene in pigs. It is a peptide hormone secreted primarily by hepatocytes. As a master regulator of iron homeostasis, it regulates iron availability including its recycling by macrophages, and releasing from hepatic stores.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH 7.4) to a concentration of 0.1-1.0 mg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
References
- Kasztura, M. et al. Hemosiderin accumulation in liver decreases iron availability in tachycardia-induced porcine congestive heart failure model. International journal of molecular sciences. 2022, 23: 1026.