This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Ovine Tumor Necrosis Factor Alpha (TNFA), N-His
Product Overview
BioVenic's Recombinant Ovine Tumor Necrosis Factor Alpha (TNFA), N-His is a recombinant protein expressed from E.coli expression system. Its predicted molecular weight is 21.0 kDa. The purity is greater than 90% (SDS-PAGE). The endotoxin level is <1 EU/μg (LAL). It can be used as a positive control or as an immunogen.
Specifications
Target Information
Tumor Necrosis Factor Alpha, a cytokine, interacts with TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR receptors. Primarily produced by macrophages, it can trigger apoptosis in specific tumor cell types. This potent pyrogen can induce fever either through direct means or by promoting interleukin-1 release. Additionally, it is associated with the onset of cachexia and, under specific circumstances, can promote cell growth and differentiation.
Shipping and Storage
This product is shipped with dry ice. Avoid repeated freezing and thawing. Store for 4 weeks at 2-8°C, for 12 months at -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH 7.4) to a concentration of 0.1-1.0 mg/mL. Aliquote the reconstituted solution to minimise freeze-thaw cycles.