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Recombinant Newcastle Disease Virus Hemagglutinin-neuraminidase (HN), N-His

Cat. No.VG3F215

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Newcastle Disease Virus Hemagglutinin-neuraminidase (HN), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 51.5 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 51.5 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

HN is a multifunctional type II transmembrane glycoprotein on the NDV envelope. It mediates viral attachment by binding to sialic acid-containing receptors on host cells and possesses neuraminidase (NA) activity to remove sialic acid, preventing viral self-aggregation and facilitating progeny release. Crucially, HN triggers the Fusion (F) protein to initiate membrane fusion. As a major surface antigen, HN is a primary target for neutralizing antibodies and is the key protein used for serological classification and vaccine development against avian paramyxoviruses.

Protein Newcastle Disease Virus Hemagglutinin-neuraminidase (HN)
Protein Synonym NDV-HN; HN glycoprotein; Attachment protein HN; Sialidase; Hemagglutinin-neuraminidase protein
UniProt ID Q9PYA4

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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