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Recombinant Mycoplasma pneumoniae MG281 Protein, N-His

Cat. No.VG3F249

Product TypeVeterinary Antigens

Size

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Product Overview

BioVenic's Recombinant Mycoplasma pneumoniae MG281 Protein, N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 62.7 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Bacteria
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 62.7 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

In Mycoplasma pneumoniae, MG281 (ortholog of M. genitalium Protein M) is a potent immunoglobulin-binding protein essential for immune evasion. It acts as a "universal" antibody blocker by binding with high affinity to the conserved variable light chain of host antibodies. This interaction prevents the antibody from recognizing its target antigen, effectively neutralizing the host's humoral response. Its ability to generically block the antibody-antigen union makes it a critical virulence factor and a promising target for therapeutic intervention.

Protein Mycoplasma pneumoniae MG281 Protein
Protein Synonym Protein M; MPN400; Uncharacterized protein MG281 homolog; MP438
UniProt ID P75383

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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