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Recombinant Mouse Vascular Endothelial Growth Factor Receptor 2 (Kdr), N-His

Cat. No.AP4C785

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Vascular Endothelial Growth Factor Receptor 2 (Kdr), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 32.4 kDa. The purity is> 90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 90%
Endotoxin <1.0 EU per 1µg (determined by the LAL method).
Predicted Molecular Weight 32.4 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Vascular Endothelial Growth Factor Receptor 2 (KDR) is a receptor tyrosine kinase involved in angiogenesis. It is crucial for the development and maintenance of blood vessels. KDR binds to vascular endothelial growth factors (VEGFs), activating signaling pathways that promote endothelial cell proliferation, survival, and migration. These processes are essential for blood vessel formation during development and wound healing. KDR is also implicated in pathological angiogenesis, such as in cancer, where it supports tumor growth by forming new blood vessels. Targeting KDR has been explored as a therapeutic strategy to inhibit angiogenesis in cancer and other diseases.

Protein Mouse Vascular Endothelial Growth Factor Receptor 2 (Kdr)
Protein Synonym VEGFR-2; Fetal liver kinase 1; Kinase NYK; Protein-tyrosine kinase receptor flk-1
Gene ID 16542
EC No. P35918

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in ddH2O to a concentration less than or equal to 0.1mg/mL. Do not vortex. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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