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Recombinant Mouse Tumor Necrosis Factor Ligand Superfamily Member 14 (Tnfsf14), N-His
Product Overview
BioVenic's Recombinant Mouse Tumor Necrosis Factor Ligand Superfamily Member 14 (Tnfsf14), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 27.5 kDa. The purity is> 90%.
Specifications
Target Information
In mice, Tumor Necrosis Factor Ligand Superfamily Member 14 (Tnfsf14), also known as LIGHT, is a protein that plays crucial roles in immune responses and inflammation. It binds to receptors such as herpesvirus entry mediator (HVEM) and lymphotoxin-β receptor (LTβR), stimulating T cell proliferation and activation. Tnfsf14 is involved in various processes, including the regulation of T cell chemotaxis and myoblast fusion. It has been implicated in diseases like graft-versus-host disease and cicatricial entropion. Tnfsf14 also affects mitochondrial respiration and function, leading to mitochondrial dysfunction and senescence.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-0.5 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.