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Recombinant Mouse Syndecan-1 (Sdc1), N-His-GST
Product Overview
BioVenic's Recombinant Mouse Syndecan-1 (Sdc1), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 54.2 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Syndecan-1 (Sdc1) is a key heparan sulfate proteoglycan integral to cell signaling and matrix interactions. It is expressed on epithelial cells and plays crucial roles in wound healing, cell adhesion, migration, and fibrosis. Sdc1 mediates interactions with extracellular matrix proteins like collagen and fibronectin, and it acts as a coreceptor for growth factors such as VEGF and TGF-β. In disease contexts, Sdc1 is implicated in cancer progression, where it forms complexes with integrins and growth factor receptors to promote tumor growth and metastasis. Soluble Sdc1, released through cleavage, can act as a decoy receptor to modulate signaling pathways and is used as a biomarker for cancer progression.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.