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Recombinant Mouse Solute Carrier Family 2, Facilitated Glucose Transporter Member 4 (Slc2a4), N-His-GST
Product Overview
BioVenic's Recombinant Mouse Solute Carrier Family 2, Facilitated Glucose Transporter Member 4 (Slc2a4), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 37.6 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Solute Carrier Family 2, Facilitated Glucose Transporter Member 4 (Slc2a4), also known as GLUT4, is a key glucose transporter involved in insulin-regulated glucose uptake. It is predominantly expressed in insulin-sensitive tissues such as skeletal muscle, cardiac muscle, and adipose tissue. GLUT4 is stored in intracellular vesicles and translocates to the plasma membrane in response to insulin stimulation, facilitating glucose entry into cells. This process is crucial for maintaining glucose homeostasis and is often studied in the context of type 2 diabetes mellitus. In mouse models, GLUT4 is used to investigate the molecular mechanisms underlying insulin resistance and glucose intolerance.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.