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Recombinant Mouse Sodium-Dependent Serotonin Transporter (Slc6a4), N-His
Product Overview
BioVenic's Recombinant Mouse Sodium-Dependent Serotonin Transporter (Slc6a4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 20.3 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Sodium-Dependent Serotonin Transporter (Slc6a4) is a crucial protein responsible for the reuptake of serotonin (5-HT) from the synaptic cleft into presynaptic neurons. This process terminates serotonin signaling and regulates synaptic levels of the neurotransmitter. Slc6a4 plays a vital role in modulating mood, anxiety, and cognitive functions. In mouse models, alterations in Slc6a4 activity or expression are linked to behavioral changes and increased susceptibility to stress and depression. Additionally, Slc6a4 is a target for selective serotonin reuptake inhibitors (SSRIs), which are commonly used antidepressants. Proper functioning of Slc6a4 is essential for maintaining serotonin homeostasis and overall mental health.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.