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Recombinant Mouse Sestrin-2 (Sesn2), N-His
Product Overview
BioVenic's Recombinant Mouse Sestrin-2 (Sesn2), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 53.7 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Sestrin-2 (Sesn2) is a stress-responsive protein that plays a crucial role in maintaining cellular homeostasis under various stress conditions, such as oxidative stress, hypoxia, and DNA damage. It is a downstream target of p53 and is involved in the regulation of autophagy, mitochondrial function, and redox balance. Sesn2 helps protect cells from metabolic stress and promotes cell survival by activating AMPK and inhibiting mTORC1. In the context of muscle atrophy, Sesn2 is involved in the regulation of muscle mass and function through the AMPK pathway.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.