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Recombinant Mouse Resistin (Retn), N-His
Product Overview
BioVenic's Recombinant Mouse Resistin (Retn), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 13.9 kDa. The purity is> 90%.
Specifications
Target Information
In mice, Resistin (Retn) is a protein primarily expressed in adipocytes and plays a significant role in metabolic regulation and inflammation. Retn is linked to insulin resistance and obesity, with elevated levels observed in these conditions. It can induce hepatic insulin resistance and promote inflammation, particularly in chronic inflammatory states such as obesity and type 2 diabetes. Retn is also involved in the regulation of glucose homeostasis and has been implicated in conditions like atherosclerosis and chronic kidney disease. In experimental models, Retn deficiency improves insulin sensitivity, while its overexpression exacerbates metabolic disorders. Overall, Retn is a key factor in understanding the pathophysiology of metabolic and inflammatory diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.