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Recombinant Mouse Protocadherin-15 (Pcdh15), N-His
Product Overview
BioVenic's Recombinant Mouse Protocadherin-15 (Pcdh15), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 29.0 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Protocadherin-15 (Pcdh15) is a member of the cadherin superfamily of cell adhesion molecules. It plays a crucial role in the development and function of sensory organs, particularly in the formation and maintenance of stereocilia in the inner ear. Pcdh15 is essential for hearing and balance, as it helps maintain the structural integrity of hair cells and their associated stereocilia. Mutations in Pcdh15 can lead to hearing loss and vestibular dysfunction. In mouse models, Pcdh15 deficiency results in severe hearing impairment and balance disorders due to the disorganization of stereocilia.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.