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Recombinant Mouse Protein FAM3B (Fam3b), N-His
Product Overview
BioVenic's Recombinant Mouse Protein FAM3B (Fam3b), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 26.6 kDa. The purity is>95%.
Specifications
Target Information
Mouse FAM3B (Fam3b), also known as pancreatic-derived factor (PANDER), is a secreted glycoprotein highly expressed in the endocrine pancreas and involved in glucose metabolism and insulin secretion. It acts as a pro-apoptotic factor for pancreatic islet cells and promotes gluconeogenesis and lipogenesis in hepatocytes by co-activating FOXO1. In cancer, FAM3B is associated with poor prognosis and promotes tumor progression, invasion, and metastasis in various cancers, including breast and gastrointestinal tumors. It also enhances chemoresistance in gastric cancer cells by inducing epithelial-mesenchymal transition. FAM3B's roles in metabolic regulation and oncogenesis make it a potential therapeutic target.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.