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Recombinant Mouse Proliferation Marker Protein Ki-67 (Mki67), N-His

Cat. No.AP4C896

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Proliferation Marker Protein Ki-67 (Mki67), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 30.6 kDa. The purity is> 90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 90%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 30.6 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Proliferation Marker Protein Ki-67 (Mki67) is a nuclear protein that is widely used as a marker for cell proliferation. It is expressed in cells that are actively cycling through the cell cycle, particularly in the G1, S, G2, and M phases. Mki67 is not detectable in quiescent (G0) cells. In mouse models, Mki67 is used to assess the rate of cell division in various tissues, including the thymus, spleen, and bone marrow. It is also a valuable tool in cancer research, where it helps to determine the proliferative capacity of tumor cells. High levels of Mki67 expression are often associated with more aggressive cancers and poorer prognosis. Additionally, Mki67 is involved in the regulation of cell cycle progression and is essential for maintaining the integrity of the cell cycle.

Protein Mouse Proliferation Marker Protein Ki-67 (Mki67)
Protein Synonym Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67 homolog; Antigen Ki67 homolog; Mki67
Gene ID 17345
EC No. E9PVX6

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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