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Recombinant Mouse Programmed Cell Death 1 Ligand 1 (CD274), N-His
Product Overview
BioVenic's Recombinant Mouse Programmed Cell Death 1 Ligand 1 (CD274), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 31.2 kDa. The purity is> 80%.
Specifications
Target Information
Mouse Programmed Cell Death 1 Ligand 1 (CD274) is a protein expressed on various immune cells and some non-immune cells. CD274 binds to PDCD1 on T cells, delivering inhibitory signals that suppress T cell function. This interaction is crucial for maintaining immune homeostasis and preventing excessive immune responses. CD274 is a central target in cancer immunotherapy, where inhibitors of this pathway have shown significant efficacy in enhancing tumor-specific immune responses.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.