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Recombinant Mouse Progonadoliberin-1 (Gnrh1), N-His
Product Overview
BioVenic's Recombinant Mouse Progonadoliberin-1 (Gnrh1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 14.8 kDa. The purity is> 97%.
Specifications
Target Information
In mice, Progonadoliberin-1 (Gnrh1) is a critical neuropeptide that regulates the hypothalamic-pituitary-gonadal axis, playing a central role in reproductive development and function. Gnrh1 is synthesized and released in a pulsatile fashion from neurons in the hypothalamus, stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. These hormones are essential for regulating the reproductive cycle and sex steroid secretion from the gonads. Gnrh1 is also involved in various physiological processes, including immune regulation and gastrointestinal motility. Mutations in the Gnrh1 gene have been associated with hypogonadotropic hypogonadism, a condition characterized by impaired reproductive function. Gnrh1 is widely used in research to study reproductive biology, neuroendocrine regulation, and the development of therapeutic strategies for reproductive disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.