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Recombinant Mouse Phospholipid-Transporting ATPase ABCA1 (Abca1), N-His
Product Overview
BioVenic's Recombinant Mouse Phospholipid-Transporting ATPase ABCA1 (Abca1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 30.1 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Phospholipid-Transporting ATPase ABCA1 (Abca1) is a key protein involved in lipid metabolism and cholesterol efflux. It plays a crucial role in the reverse cholesterol transport (RCT) pathway, facilitating the transport of cholesterol from peripheral tissues to the liver for excretion. Abca1 is highly expressed in macrophages and endothelial cells, where it promotes the formation of high-density lipoprotein (HDL) particles. This protein is essential for maintaining cholesterol homeostasis and preventing the accumulation of cholesterol in tissues. Abnormal expression or function of Abca1 has been implicated in various diseases, including atherosclerosis and cardiovascular diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in ddH2O to a concentration less than or equal to 0.1mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.