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Recombinant Mouse Peroxisome Proliferator-Activated Receptor Gamma (Pparg), N-His
Product Overview
BioVenic's Recombinant Mouse Peroxisome Proliferator-Activated Receptor Gamma (Pparg), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 15.6 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Peroxisome Proliferator-Activated Receptor Gamma (Pparg) is a ligand-activated transcription factor belonging to the nuclear receptor superfamily. It plays a crucial role in regulating adipocyte differentiation, lipid metabolism, and glucose homeostasis. Pparg forms heterodimers with retinoid X receptors (RXRs) and binds to peroxisome proliferator response elements (PPREs) in the DNA to regulate gene expression. In mice, Pparg is highly expressed in adipose tissue, muscle, and the liver, where it promotes adipogenesis and enhances insulin sensitivity. Mutations in Pparg can lead to lipodystrophy and insulin resistance. Additionally, Pparg has been implicated in the pathology of various diseases, including obesity, diabetes, and atherosclerosis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.