This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Recombinant Mouse Peroxisome Proliferator-Activated Receptor Alpha (Ppara), N-His-GST
Product Overview
BioVenic's Recombinant Mouse Peroxisome Proliferator-Activated Receptor Alpha (Ppara), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 46.9 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Peroxisome Proliferator-Activated Receptor Alpha (Ppara) is a master regulator of fatty acid oxidation (FAO) and systemic metabolic homeostasis, belonging to the nuclear receptor superfamily. When activated by its ligands, such as endogenous fatty acids or exogenous fibrate drugs, Ppara heterodimerizes with the retinoid X receptor, binds to the PPAR response element on the promoter of target genes, and promotes fatty acid uptake, transport, and β-oxidation. Ppara plays a crucial role in maintaining energy metabolism and preventing metabolic disorders. In mouse models, Ppara is highly expressed in tissues such as the liver, heart, and adipose tissue, where it regulates lipid metabolism and glucose homeostasis. Abnormal expression or mutations in Ppara have been implicated in various diseases, including diabetes, obesity, and cardiovascular diseases.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.