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Recombinant Mouse Neuronal Migration Protein Doublecortin (Dcx), N-His
Product Overview
BioVenic's Recombinant Mouse Neuronal Migration Protein Doublecortin (Dcx), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 44.3 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Neuronal Migration Protein Doublecortin (Dcx) is a microtubule-associated protein crucial for neuronal migration and development. It promotes microtubule polymerization and stability, facilitating the movement of neurons during brain development. DCX is particularly important for maintaining the bipolar morphology of migrating neurons, and its deficiency can lead to increased neurite branching and disorganized migration. In mouse models, DCX knockout results in specific brain structural abnormalities, such as disorganization of the hippocampus, but not always in cortical layering defects. DCX also regulates tubulin polyglutamylation, which affects neurite density and branching.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.