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Recombinant Mouse Metalloproteinase Inhibitor 4 (Timp4), N-His

Cat. No.AP4C122

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Metalloproteinase Inhibitor 4 (Timp4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 22.6 kDa. The purity is>95%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity >95%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 22.6 kDa
Physical State Lyophilized
Formulation 20 mM Tris, 150 mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Mouse Metalloproteinase Inhibitor 4 (Timp4) is a tissue inhibitor of metalloproteinases that primarily inhibits matrix metalloproteinases. It plays a significant role in the cardiovascular system by regulating cardiomyocyte proliferation and apoptosis. Timp4 is associated with diseases such as myocardial infarction and heart failure. Studies have shown that changes in Timp4 expression correlate with cardiac remodeling and functional impairment, indicating its potential as a therapeutic target in cardiovascular diseases.

Protein Mouse Metalloproteinase Inhibitor 4 (Timp4)
Protein Synonym Tissue inhibitor of metalloproteinases 4; TIMP-4
Gene ID 110595
EC No. Q9JHB3

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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