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Recombinant Mouse Metalloproteinase Inhibitor 3 (Timp3), N-His
Product Overview
BioVenic's Recombinant Mouse Metalloproteinase Inhibitor 3 (Timp3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 23.3 kDa. The purity is>80%.
Specifications
Target Information
Mouse Metalloproteinase Inhibitor 3 (Timp3) is a tissue inhibitor of metalloproteinases that inhibits matrix metalloproteinases, ADAMs, and ADAMTSs. It plays a crucial role in regulating extracellular matrix stability, suppressing inflammation, and exhibiting antitumor properties. Timp3 indirectly reduces TNF levels by inhibiting ADAM17, thereby modulating inflammatory responses. Additionally, it inhibits cell proliferation, migration, and angiogenesis, making it a potential biomarker in various disease models, including cancer and inflammatory disorders.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.