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Recombinant Mouse Leucine-Rich HEV Glycoprotein (Lrg1), N-His-GST
Product Overview
BioVenic's Recombinant Mouse Leucine-Rich HEV Glycoprotein (Lrg1), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 53.0 kDa. The purity is> 80%.
Specifications
Target Information
Mouse Leucine-Rich HEV Glycoprotein (Lrg1) is a multifunctional protein primarily produced by hepatocytes and neutrophils. It modulates various signaling pathways, particularly the TGF-β signaling cascade. In mouse models, Lrg1 promotes angiogenesis and lymphangiogenesis by upregulating VEGF and its receptors. It also plays a role in acute pancreatitis, where its inhibition accelerates recovery by inducing CCK1R expression via the TGFβ/ALK5/AKT pathway.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in ddH2O to a concentration of 0.1-0.2 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.