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Recombinant Mouse L-Lactate Dehydrogenase B Chain (Ldhb), N-His
Product Overview
BioVenic's Recombinant Mouse L-Lactate Dehydrogenase B Chain (Ldhb), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 37.8 kDa. The purity is> 90%.
Specifications
Target Information
Mouse L-Lactate Dehydrogenase B Chain (Ldhb) is a key enzyme involved in the interconversion of pyruvate and lactate, playing a crucial role in cellular metabolism and energy production. In cancer, LDHB is often upregulated and has been implicated in promoting tumor growth and metastasis by supporting metabolic homeostasis and DNA damage repair. For instance, in non-small cell lung cancer (NSCLC), LDHB silencing enhances the effects of radiotherapy by impairing nucleotide metabolism and promoting persistent DNA damage.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.