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Recombinant Mouse Interleukin-6 Receptor Subunit Alpha (IL-6RA), C-His

Cat. No.AP2C942

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Interleukin-6 Receptor Subunit Alpha (IL-6RA), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 50.5 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 50.5 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse Interleukin-6 Receptor Subunit Alpha (IL-6RA) is a receptor subunit for interleukin-6 (IL-6). It is involved in mediating the effects of IL-6, which plays roles in inflammation, immune response, and hematopoiesis. IL-6RA is expressed on various cells and forms a complex with IL-6 and the signal-transducing beta subunit gp130. This complex activates signaling pathways like JAK-STAT and MAPK, regulating gene expression related to inflammation and immune responses. IL-6RA is implicated in various inflammatory diseases and has been targeted therapeutically in conditions like rheumatoid arthritis.

Protein Mouse Interleukin-6 Receptor Subunit Alpha (IL-6RA)
Protein Synonym IL-6 receptor subunit alpha; IL-6R subunit alpha; IL-6R-alpha; IL-6RA
Gene ID 16194
UniProt ID P22272

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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