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Recombinant Mouse Interleukin-25 (Il25), N-His-GST
Product Overview
BioVenic's Recombinant Mouse Interleukin-25 (Il25), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 43.4 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Interleukin-25 (Il25) is a cytokine belonging to the IL-17 family, which primarily promotes type 2 immune responses. It is highly expressed in Th2-polarized cells and epithelial cells of the gastrointestinal tract. Il25 induces the production of IL-4, IL-5, and IL-13, leading to Th2-skewed inflammation. This cytokine plays a crucial role in immune regulation, particularly in allergic airway inflammation and intestinal helminth infections. In mouse models, Il25 has been shown to enhance allergic airway inflammation by amplifying a Th2 cell-dependent pathway. Additionally, Il25 can suppress Th1 and Th17 responses, contributing to immune homeostasis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.