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Recombinant Mouse Interleukin-1 alpha (Il1a), N-His
Product Overview
BioVenic's Recombinant Mouse Interleukin-1 alpha (Il1a), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.7 kDa. The purity is>90%.
Specifications
Target Information
Mouse Interleukin-1 alpha (IL-1α) is a pro-inflammatory cytokine produced by various cell types, including monocytes, macrophages, and epithelial cells. It binds to the interleukin-1 receptor type 1 (IL1R1), activating signaling pathways like NF-κB and MAPK, leading to the production of inflammatory mediators. IL-1α is involved in processes such as fever induction, acute-phase reactions, and immune cell recruitment. It has been implicated in the pathogenesis of inflammatory and autoimmune diseases. IL-1α also plays a role in tissue repair and regeneration.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL.Aliquot the reconstituted solution to minimize freeze-thaw cycles.