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Recombinant Mouse Interferon Regulatory Factor 1 (Irf1), N-His-GST

Cat. No.AP4C804

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Interferon Regulatory Factor 1 (Irf1), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 63.1 kDa. The purity is> 95%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 95%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 63.1 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.

Target Information

Mouse Interferon Regulatory Factor 1 (Irf1) is a transcription factor that plays a crucial role in the regulation of immune responses, particularly in the production of type I interferons (IFN-I) and other pro-inflammatory cytokines. Irf1 is essential for the activation of dendritic cells (DCs) and the induction of IL-12, a key cytokine for Th1 cell differentiation. It also regulates the development and function of CD8+ T cells, enhancing their cytotoxic activity. In addition, Irf1 is involved in the regulation of innate immunity against viral infections, promoting the expression of antiviral genes and enhancing the activation of natural killer (NK) cells. Abnormal expression of Irf1 has been implicated in various diseases, including cancer and autoimmune disorders.

Protein Mouse Interferon Regulatory Factor 1 (Irf1)
Protein Synonym IRF-1; Irf1
Gene ID 16362
EC No. P15314

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS or others. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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