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Recombinant Mouse Integrin Alpha-3 (Itga3), N-His

Cat. No.AP4C767

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Integrin Alpha-3 (Itga3), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 26.8 kDa. The purity is> 95%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 95%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 26.8 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Integrin Alpha-3 (Itga3) is a subunit of the integrin receptor family, which plays a crucial role in cell adhesion, migration, and signaling. It forms a heterodimer with the integrin beta-1 subunit to create the α3β1 integrin, which binds to extracellular matrix components such as laminin and collagen. In mouse models, Itga3 is highly expressed in epithelial cells, where it is involved in maintaining tissue integrity and facilitating wound healing. Abnormal expression or function of Itga3 has been implicated in various diseases, including cancer, where it can promote tumor invasion and metastasis by enhancing cell adhesion and migration.

Protein Mouse Integrin Alpha-3 (Itga3)
Protein Synonym CD49 antigen-like family member C; Galactoprotein B3; VLA-3 subunit alpha
Gene ID 16400
EC No. Q62470

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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