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Recombinant Mouse IgG Receptor FcRn Large Subunit p51 (FCGRT), C-His

Cat. No.AP2C976

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse IgG Receptor FcRn Large Subunit p51 (FCGRT), C-His is a recombinant protein expressed from Human Cells. Its predicted molecular weight is 40.1 kDa. The purity is>90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System Human Cells
Purity >90%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 40.1 kDa
Physical State Lyophilized
Formulation 0.01 mol/L PBS (pH 7.2) containing 0.2% (w/v) Procline-300.

Target Information

Mouse IgG Receptor FcRn Large Subunit p51 (FCGRT) is a subunit of the neonatal Fc receptor (FcRn), which plays a crucial role in IgG homeostasis and antibody transport. FCGRT is involved in prolonging the half-life of IgG antibodies by recycling them in endothelial cells. This receptor also facilitates the transport of maternal IgG antibodies across the placenta to the fetus, providing immune protection. FCGRT has been implicated in various immune-related processes and may be a therapeutic target for modulating antibody responses in diseases.

Protein Mouse IgG Receptor FcRn Large Subunit p51 (FCGRT)
Protein Synonym FcRn; IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor
Gene ID 14132
UniProt ID Q61559

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -20°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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