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Recombinant Mouse Glutamate Receptor Ionotropic, NMDA 2A (Grin2a)
Product Overview
BioVenic's Recombinant Mouse Glutamate Receptor Ionotropic, NMDA 2A (Grin2a) is a recombinant protein expressed from E.coli. Its predicted molecular weight is n/a. The purity is> 80%.
Specifications
Target Information
Mouse Glutamate Receptor Ionotropic, NMDA 2A (Grin2a) is a subunit of the NMDA receptor, a type of ionotropic glutamate receptor that plays a crucial role in synaptic transmission and plasticity. It is highly expressed in the brain and is essential for learning and memory processes. Grin2a contributes to the regulation of long-term potentiation (LTP) and long-term depression (LTD), which are fundamental mechanisms underlying synaptic plasticity. In mouse models, mutations in Grin2a can lead to cognitive deficits and behavioral abnormalities. Additionally, Grin2a is implicated in neurodevelopmental disorders and neurodegenerative diseases, highlighting its importance in maintaining neuronal function and synaptic integrity.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.