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Recombinant Mouse Ficolin-1 (Fcn1), N-His
Product Overview
BioVenic's Recombinant Mouse Ficolin-1 (Fcn1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 35.5 kDa. The purity is> 95%.
Specifications
Target Information
Mouse Ficolin-1 (Fcn1) is a key innate immune protein that functions as a pattern recognition molecule, binding to acetylated carbohydrates on pathogens such as bacteria and fungi. It activates the lectin complement pathway through MASPs (Mannan-binding lectin-associated serine proteases), leading to pathogen opsonization, phagocytosis, and inflammatory responses. Additionally, Fcn1 contributes to immune homeostasis by aiding in the clearance of apoptotic cells. Produced mainly by myeloid cells, it plays a protective role in infections (e.g., Streptococcus pneumoniae) and may influence inflammatory and autoimmune processes. Its functions highlight its importance in bridging innate immunity and pathogen defense.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.