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Recombinant Mouse Endothelin-1 (Edn1), N-His

Cat. No.AP4C225

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Endothelin-1 (Edn1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 21.0 kDa. The purity is>95%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity >95%
Endotoxin < 1.0 EU/μg
Predicted Molecular Weight 21.0 kDa
Physical State Lyophilized
Formulation 100 mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Mouse Endothelin-1 (Edn1) is a member of the endothelin family, known for its potent vasoconstrictive properties. It plays a critical role in maintaining normal heart function, craniofacial development, and melanocyte homeostasis. Edn1 regulates melanocyte proliferation, migration, and DNA repair in response to UV radiation. It also influences bone biology and is involved in signaling pathways that promote bone matrix synthesis and mineralization. Additionally, Edn1 is essential for proper cardiac function, particularly in controlling superoxide levels and matrix metalloproteinase expression.

Protein Mouse Endothelin-1 (Edn1)
Protein Synonym ET-1; Preproendothelin-1; Big endothelin-1
Gene ID 13614
EC No. P22387

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in deionized sterile water to a concentration of 0.1-0.5 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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