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Recombinant Mouse Endoplasmic Reticulum Chaperone BiP (Hspa5), N-His

Cat. No.AP4C915

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Endoplasmic Reticulum Chaperone BiP (Hspa5), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 24.8 kDa. The purity is> 90%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 90%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 24.8 kDa
Physical State Lyophilized
Formulation 20 mM Tris, 150 mM NaCl, pH8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Target Information

Mouse Endoplasmic Reticulum Chaperone BiP (Hspa5) is a crucial molecular chaperone located in the endoplasmic reticulum (ER). It assists in the proper folding of nascent proteins and prevents aggregation of misfolded proteins. BiP also plays a key role in the unfolded protein response (UPR), helping cells to cope with ER stress. In addition, it is involved in maintaining calcium homeostasis within the ER. BiP is essential for cellular homeostasis and is implicated in various diseases, including neurodegenerative disorders and cancer, due to its role in protein quality control.

Protein Mouse Endoplasmic Reticulum Chaperone BiP (Hspa5)
Protein Synonym 78 kDa glucose-regulated protein; Binding-immunoglobulin protein; Heat shock protein 70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein; Hspa5; Grp78
Gene ID 14828
EC No. P20029

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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