Recombinant Mouse Death-Associated Protein Kinase 3 (Dapk3), N-His

Mouse Death-Associated Protein Kinase 3 (Dapk3) is a serine/threonine kinase involved in the regulation of apoptosis and autophagy. It plays a crucial role in mediating cell death pathways, particularly in response to stress signals such as DNA damage and oxidative stress. Dapk3 can induce apoptosis by phosphorylating and regulating the activity of various proteins involved in cell survival and death. In mouse models, Dapk3 deficiency leads to increased cell survival and resistance to stress-induced apoptosis. Additionally, Dapk3 is implicated in the regulation of autophagy, a process that helps cells recycle damaged organelles and maintain cellular homeostasis. Its functions highlight the importance of Dapk3 in maintaining cellular integrity and responding to stress.