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Recombinant Mouse Corticosteroid-Binding Globulin (Serpina6), N-His
Product Overview
BioVenic's Recombinant Mouse Corticosteroid-Binding Globulin (Serpina6), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 18.1 kDa. The purity is> 97%.
Specifications
Target Information
Mouse Corticosteroid-Binding Globulin (Serpina6) is a plasma protein that binds and transports corticosteroids, primarily cortisol, in the bloodstream. It plays a crucial role in regulating the bioavailability of corticosteroids, thereby modulating the stress response and immune function. Serpina6 is synthesized in the liver and secreted into the plasma, where it helps maintain corticosteroid homeostasis. Abnormal levels of Serpina6 can lead to dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and contribute to conditions such as Cushing's syndrome and Addison's disease. In mouse models, Serpina6 has been shown to influence corticosteroid distribution and metabolism, highlighting its importance in maintaining endocrine balance.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.