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Recombinant Mouse Coagulation Factor XIII B Chain (F13b), N-His
Product Overview
BioVenic's Recombinant Mouse Coagulation Factor XIII B Chain (F13b), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 25.0 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Coagulation Factor XIII B Chain (F13b) is a component of the plasma form of Factor XIII, a heterotetrameric protein complex that plays a critical role in the coagulation cascade by stabilizing blood clots. F13b is essential for the stability and function of the Factor XIII complex. It forms a tetramer with two catalytic A subunits (F13a) and two B subunits (F13b), known as FXIII-A2B2. The B subunit acts as a carrier protein, stabilizing the A subunit and facilitating its binding to fibrinogen. During clot formation, thrombin cleaves the activation peptide from the A subunit, activating the complex into FXIIIa, which then cross-links fibrin monomers, enhancing clot stability. F13b deficiency can lead to bleeding disorders, highlighting its importance in hemostasis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.