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Recombinant Mouse C-type Natriuretic Peptide (Nppc), N-His-GST
Product Overview
BioVenic's Recombinant Mouse C-type Natriuretic Peptide (Nppc), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 42.7 kDa. The purity is> 95%.
Specifications
Target Information
Mouse C-type Natriuretic Peptide (Nppc) is a key regulator of electrolyte-fluid balance and vascular tone. Unlike ANP and BNP, CNP does not have strong diuretic effects but is a potent arterial and venous dilator. It plays a crucial role in bone growth by regulating endochondral ossification. Nppc knockout mice exhibit growth defects and dwarfism. CNP also affects the cardiovascular system by lowering blood pressure and acting as an endothelium-derived hyperpolarizing factor. Its role in diseases like Lesch-Nyhan syndrome and certain cancers is under investigation, highlighting its potential as a therapeutic target.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in PBS or others. Aliquot the reconstituted solution to minimize freeze-thaw cycles.