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Recombinant Mouse C-C Motif Chemokine 5 (Ccl5), N-His-GST
Product Overview
BioVenic's Recombinant Mouse C-C Motif Chemokine 5 (Ccl5), N-His-GST is a recombinant protein expressed from E.coli. Its predicted molecular weight is 37.9 kDa. The purity is>95%.
Specifications
Target Information
Mouse C-C Motif Chemokine 5 (CCL5) is a chemokine that plays a role in immune cell migration and activation. It binds to chemokine receptors such as CCR1, CCR3, and CCR5, promoting the recruitment of immune cells like T cells and macrophages to sites of inflammation. CCL5 is involved in various inflammatory processes and has been implicated in diseases such as hypertension, atherosclerosis, and autoimmune disorders. It contributes to vascular inflammation and endothelial dysfunction by activating signaling pathways like NF-κB and NADPH oxidase.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.