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Recombinant Mouse Aquaporin-4 (Aqp4), N-His
Product Overview
BioVenic's Recombinant Mouse Aquaporin-4 (Aqp4), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 17.7 kDa. The purity is> 90%.
Specifications
Target Information
Mouse Aquaporin-4 (AQP4) is a water-specific channel protein primarily expressed in the brain, particularly in astrocytes and the glial limitans. It plays a critical role in maintaining brain fluid homeostasis, facilitating water transport across the blood-brain barrier (BBB), and supporting the glymphatic system, which clears metabolic waste from the brain. AQP4 is also involved in various neurological processes, including neuroinflammation, brain edema, and neurodegenerative diseases such as Alzheimer's disease and multiple sclerosis.
Shipping and Storage
This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 20 mM Tris, 150 mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.