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Recombinant Mouse Aldehyde Dehydrogenase 1A1 (Aldh1a1), N-His

Cat. No.AP4C994

Product TypeAnimal Proteins

Size

Product Overview

BioVenic's Recombinant Mouse Aldehyde Dehydrogenase 1A1 (Aldh1a1), N-His is a recombinant protein expressed from E.coli. Its predicted molecular weight is 39.0 kDa. The purity is> 97%.

Specifications

Type Recombinant Protein
Species Mouse
Expression System E.coli
Purity > 97%
Endotoxin <1.0 EU per 1µg (determined by the LAL method)
Predicted Molecular Weight 39.0 kDa
Physical State Lyophilized
Formulation PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Target Information

Mouse Aldehyde Dehydrogenase 1A1 (Aldh1a1) is an enzyme that catalyzes the oxidation of retinaldehyde to retinoic acid, a key regulator of cell differentiation and development. Aldh1a1 is highly expressed in tissues such as the liver and retina. In the liver, it contributes to bile acid synthesis and detoxification. In the retina, it is essential for the production of retinoic acid, which is crucial for vision. Aldh1a1 also plays a role in embryonic development, regulating gene expression and tissue morphogenesis. In mouse models, Aldh1a1 deficiency leads to developmental abnormalities and impaired vision. Additionally, Aldh1a1 is involved in metabolic processes and has potential roles in cancer, where it can influence cell proliferation and differentiation.

Protein Mouse Aldehyde Dehydrogenase 1A1 (Aldh1a1)
Protein Synonym 3-deoxyglucosone dehydrogenase; ALDH-E1
Gene ID 11668
EC No. P24549

Shipping and Storage

This product is shipped with ice packs. Lyophilized protein can be stored at -80°C for 1 year. After reconstitution, the protein solution can be stored at 2-8°C for 2-7 days.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Reconstitute in 10 mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Aliquot the reconstituted solution to minimize freeze-thaw cycles.
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