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Recombinant Monkeypox Virus B16R Protein (MPXV B16R), N-His
Product Overview
BioVenic's Recombinant Monkeypox Virus B16R Protein (MPXV B16R), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 40.2 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
B16R is a secreted immunomodulatory glycoprotein that acts as a decoy receptor for host Type I interferons (IFN-α/β). By binding to these interferons with high affinity, B16R prevents them from interacting with their native cellular receptors, thereby neutralizing the host's primary antiviral signaling pathway. This blockade inhibits the induction of interferon-stimulated genes (ISGs) and suppresses the activation of an effective innate immune response. Due to its potent role in viral virulence and immune evasion, B16R is a significant target for therapeutic inhibitors and diagnostic research.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.