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Recombinant Lumpy Skin Disease Virus EEV Glycoprotein (LSDV122), N-His
Product Overview
BioVenic's Recombinant Lumpy Skin Disease Virus EEV Glycoprotein (LSDV122), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 17.1 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
LSDV122 is a critical immunomodulatory glycoprotein found in the Lumpy Skin Disease Virus. Recent studies identify it as a potent antagonist of Type I Interferon (IFN-I) signaling. It works by interacting with both IFNAR1 and IFNAR2 subunits, preventing the assembly of the receptor complex and the subsequent activation of the JAK-STAT pathway. This suppression of host innate immunity is essential for viral virulence and efficient replication. Due to its role in immune evasion, LSDV122 is a primary target for the development of live-attenuated vaccines.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
