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Recombinant Lumpy Skin Disease Virus EEV Glycoprotein (LSDV122), N-His

Cat. No.VG3F198

Product TypeVeterinary Antigens

Size

Product Overview

BioVenic's Recombinant Lumpy Skin Disease Virus EEV Glycoprotein (LSDV122), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 17.1 kDa. The purity is>90% (SDS-PAGE).

Specifications

Type Recombinant Protein
Species Virus
Expression System E.coli Expression System
Purity >90% (SDS-PAGE)
Predicted Molecular Weight 17.1 kDa
Physical State Lyophilized
Formulation PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Target Information

LSDV122 is a critical immunomodulatory glycoprotein found in the Lumpy Skin Disease Virus. Recent studies identify it as a potent antagonist of Type I Interferon (IFN-I) signaling. It works by interacting with both IFNAR1 and IFNAR2 subunits, preventing the assembly of the receptor complex and the subsequent activation of the JAK-STAT pathway. This suppression of host innate immunity is essential for viral virulence and efficient replication. Due to its role in immune evasion, LSDV122 is a primary target for the development of live-attenuated vaccines.

Protein Lumpy Skin Disease Virus EEV Glycoprotein (LSDV122)
Protein Synonym LSDV122; LSDV-122; Putative EEV Glycoprotein; Interferon Antagonist LSDV122; Capripoxvirus LSDV122

Shipping and Storage

This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

User Note

  1. Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.
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