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Recombinant Lake Victoria Marburgvirus Envelope Glycoprotein 2 (GP2), N-GST and C-His
Product Overview
BioVenic's Recombinant Lake Victoria Marburgvirus Envelope Glycoprotein 2 (GP2), N-GST and C-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 51.1 KDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
GP2 is the membrane-proximal subunit of the Marburgvirus spike complex, generated via furin-cleavage of the GP0 precursor. It serves as the essential Type I viral fusion machine, anchoring the glycoprotein to the viral envelope. Following receptor binding and endosomal cathepsin priming, GP2 undergoes a dramatic conformational shift to insert its fusion peptide into the host membrane. This process facilitates the critical pore formation required for releasing the viral nucleocapsid into the host cytoplasm during infection.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.