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Recombinant Influenza A H5N1 Hemagglutinin (HA), N-His
Product Overview
BioVenic's Recombinant Influenza A H5N1 Hemagglutinin (HA), N-His is a recombinant protein expressed from E.coli Expression System. Its predicted molecular weight is 59.9 kDa. The purity is>90% (SDS-PAGE).
Specifications
Target Information
Hemagglutinin is the major surface glycoprotein and primary virulence factor of the highly pathogenic avian influenza (HPAI) H5N1 virus. It mediates viral entry by specifically binding to alpha 2,3-linked sialic acid receptors, primarily found in the avian gastrointestinal tract and the human lower respiratory tract. Following endocytosis, the HA2 subunit undergoes a low-pH-triggered conformational change to facilitate membrane fusion. Due to its role in host range adaptation and high mortality rates, H5 HA is a critical target for pandemic preparedness, neutralizing antibody therapy, and vaccine design.
Shipping and Storage
This product is shipped with gel ice bags. Avoid repeated freezing and thawing. Store for 12 months at -20°C or -80°C.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- Always centrifuge tubes before opening. Avoid mixing by vortexing or pipetting. Aliquote the reconstituted solution to minimise freeze-thaw cycles.